A imagem sugestiva "retorno do outro" ajuda a indicar o modo como a alteridade interpela no actual contexto de globalização. Esse "outro", o grande ausente da maior parte da história da filosofia ocidental, aparece com força renovada (ou, pelo menos, resiste aos embates da homo-geneização) frente à lógica económica, política e cultural, que pretende anulá-lo na imposição uniforme de um estilo de vida. O seu "retorno" abre possibilidades em várias perspectivas. Aqui apenas esboçamos o que significou este "retorno do outro" (...) na irrupção do pensamento intersubjectivo, bem como as possibilidades que abre para a relação intercultural. The suggestive image, "turn to the other", gives an indication of how alterity challenges the current context of globalisation- This "other" is the great absent in the greater part of the history of Western philosophy. It appears with renovated strength (or at least resists the pressures of homogenisation) in the face of the economic, political, and cultural logic that seeks to annul it through the uniform imposition of a given lifestyle. Its return opens possibilities of varying kinds. Here we wish only to sketch the meaning of this "turn to the other" in the irruption of the inter-subjective thought and possibilities it opens for intercultural relations. (shrink)

Epigenetic and transcriptional variability contribute to the vast diversity of cellular and organismal phenotypes and are key in human health and disease. In this review, we describe different types, sources, and determinants of epigenetic and transcriptional variability, enabling cells and organisms to adapt and evolve to a changing environment. We highlight the latest research and hypotheses on how chromatin structure and the epigenome influence gene expression variability. Further, we provide an overview of challenges in the analysis of biological variability. An (...) improved understanding of the molecular mechanisms underlying epigenetic and transcriptional variability, at both the intra- and inter-individual level, provides great opportunity for disease prevention, better therapeutic approaches, and personalized medicine. Epigenetic and transcriptional variability mediate phenotypic plasticity, enabling adaptation to changing environments. In this review, we describe the sources of inter- and intra-individual variability and discuss epigenetic regulators of gene expression variability, including DNA methylation and chromatin structure. Understanding these molecular mechanisms will improve therapeutic approaches and personalized medicine. (shrink)

Este trabajo se centra en cómo en la España de la segunda mitad del siglo XVIII con motivo de la reforma de los estudios teológicos tanto en los Seminarios –necesaria para la mejora de la formación de uno de los principales agentes del propugnado y urgente cambio religioso– como en las Universidades –en las que se quería sustituir la influencia jesuítica por otra más de acorde con las ideas regalistas– se impulsó la creación de las cátedras De locis theologicis, muchas (...) de las cuales debían seguir el tratado de Melchor Cano y otras seguir a otros tratadistas, pero teniendo presente en sus explicaciones la docta obra de Melchor Cano. También se estudiará en la reforma del Plan de Estudios de la Orden de Frailes Predicadores, así como el rechazo que de todo ello tuvo el importante ilustrado valenciano Gregorio Mayans y Ciscar. The work is about how in the Spain of the second half of the 18th century owing to the theological studies reform as much in Seminaries-necessary to the education improvement of one of the main agents of the proposed and urgent religious change-as in Universities-in which it was wanted to substitute the Jesuitical influence for another more appropriate to the regalist ideas– the creation of the Locis theologicis chairs, many of which had to follow Melchor Cano’s treatise, and other chairs had to follow other authors, was promoted; but bearing in mind in their explanations Melchior Cano’s erudite work. Such treatise will also be studied in the reform of the Order of Preacher’ curriculum, as well as the rejection of all that by the important learned Gregorio Mayans y Ciscar, native of Valencia. (shrink)

La presente reseña de Escritores viajeros. El nomadismo como poética destaca el valor de la fórmula homo viator como columna interpretativa con la que Asunción Rangel analiza la obra de cuatro poetas hispanoamericanos.

El presente trabajo investiga las tesis sobre el poder civil de Alonso de la Veracruz que buscan incorporar en la comunidad política española a los habitantes autóctonos del Nuevo Mundo, tesis que suelen relacionarse con F. de Vitoria y el tomismo español, y que últimamente son consideradas parte del republicanismo novohispano elaborado desde la periferia americana. Se busca demostrar que su propósito era aplicar una teoría de derechos naturales, sin que ello implique participación política de los indios americanos. Se analiza (...) la postura del fraile frente a la diversidad cultural y la guerra contra los indios. The paper explores Alonso de la Veracruz's theses on civil power, which sought to integrate the native inhabitants of the New World into the Spanish political community. These theses, which have usually been associated with F. de Vitoria and Spanish Thomism, have recently come to be considered part of a Novohispanic republicanism developed in the American periphery. The article seeks to show that the purpose of such theses was to apply a theory of natural rights that did not entail the political participation of the indigenous population, as well as to analyze Veracruz's position regarding cultural diversity and the war against the indigenous peoples. (shrink)

Distance education offers flexibility and accessibility to students with diverse needs and contexts. However, it is crucial to understand the factors that motivate students to choose this educational modality, especially in programs like Public Accounting, which require specific skills. The general objective of this article is to analyze the determinants in the decision to study the Public Accounting Program in a distance or virtual modality at the National Open and Distance University (UNAD). A mixed methodology is employed, supported by authors (...) such as Creswell (2014), combining quantitative and qualitative data, and using the Probit model to identify factors influencing this choice. A significant finding is that tuition cost, the Saber 11 test score and parents' education are significant variables affecting students' decisions, with tuition cost having the greatest influence on the probability of choice. (shrink)

1. Introduction to a dilemma. 2. Returning to the beginning of time. 3. From a non-existent time in classical physics to an strange destiny of time in nowadays science. 4. Time of those who want understand the reality of history. 5. What will be, then, an existent time from which we can talk about the history of time (or the time of history) denoting and "omega point"?

Resumen Este artículo analiza si en la teoría de los cuatro ethe de la modernidad capitalista, desarrollada por Bolívar Echeverría, no está contenida una debilidad de principio. Se trata de saber si para arribar a sus más altas aportaciones, esta teoría no termina pagando un precio que debiera dar que pensar. ¿Acaso renuncia a la crítica de la ideología, por lo menos en la radicalidad realizada por los autores de la Teoría crítica, inspirados en este punto originalmente por Georg Lukács?This (...) article is analyzing if in the theory of the four ethe of capitalist modernity, developed by Bolívar Echeverría, isn’t included a basic weakness. It is about understanding if for to arrive to its highest contributions, this theory is not paying a too high prize. Does it possibly renounce to the critique of ideology, at least in the radicality fulfilled by the authors of Critical theory, inspired in this point originally by Georg Lukács? (shrink)

A number of central government policy initiatives in the UK are encouraging the sharing of information between government and other partners. A relatively large amount of information is available to enhance social inclusion but this data does not always have the detail required to investigate small areas. As a result information sharing of locally generated information is increasing in the UK, particularly for issues such as health and crime where information is not readily available for Local Authorities. Legal and ethical (...) issues associated with sharing locally generated information are frequently perceived as problematical. Examples of methods and protocols to overcome these problems are reviewed. It is possible that the activities of the Cabinet Office Committee on data sharing will act as an incentive for data sharing. However, an equally important catalyst will be commitment and support across UK central government and at the local level by Chief Executives and members to the principles and benefits of information sharing for better informed policymaking. (shrink)

In the context of medical ethics, how can the concept of informed consent be effectively implemented in a traditional society such as Japan? If the need for more openness and transparency is not felt in the practice of medicine and welfare, the clients must remain under the spell of paternalistic data. Patients and health-care professionals other than doctors are taken to be "responsible for what they do but not to be accountable for their conduct" because they do not participate in (...) a decision-making process. I explore the possibility of the concept's full implementation against the particularists' and communitarian ethicists' effort to reject the universal nature of the concept. (shrink)

Watts, Sandro. “¿Puede hablarse de poesía filosófica en Platón?” Eidos [Barranquilla, Universidad del Norte], 20 (2014): 75-94.

The climate crisis has implications for the idea of justice. The paper explores this idea to inquire whether climate change wrongs animals and, if it does, how these wrongs are constitutive of an injustice. The first question is answered in the positive to then propose an answer to the second question through an account of climate injustice articulated as a problem of distribution of ecological space. On that basis, the general conclusion of the paper is that at least some harms (...) suffered by animals are constitutive of climate distributive injustices. They are cases of wrongful appropriation of ecological space, that is, of the benefits that the Earth’s life-support systems and its physical resources provide to sentient animals. These are wrongs against animals that should be condemned, prohibited and redressed. (shrink)

El objetivo consiste en analizar qué se entiende por naturaleza en Epicuro y cómo se sortean los males que se le endilgan a una sensación tenida por contraria a la práctica de la virtud. En primer lugar, se enfatiza el modo como la percepción sensible trae consigo ciertas consecuencias éticas. Luego, se presenta la estructura sistemática de naturaleza-sensación-acción en el epicureísmo y una posición moderada entre determinismo causal y arbitrariedad ética. Finalmente, se defiende el nexo entre virtud y goce sobre (...) la base del atomismo. Las conclusiones vuelven sobre el concepto de naturaleza y su relación con la percepción sensible y placentera. (shrink)